Lab Introduction & Major Research Interests
1. Function of auditory system, Hereditary hearing loss, Noise-induced hearing loss, Age-related hearing loss
2. Auditory speech performance in hearing-impaired subjects
3. Cochlear implantation
4. Regeneration of peripheral auditory nervous system.
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Recent Representative Publication ( * corresponding author)
1. Cheng YF, Chan YH, Hu CJ, Lu YC, Saeki T, Hosoya M, Saegusa C, Fujioka M, Okano H, Weng SM, Hsu CJ, Chang KH, Wu CC, 2019. Generation of a human iPS cell line (CGMH.SLC26A4919-2) from a Pendred syndrome patient carrying SLC26A4 c.919-2A>G splice-site mutation. Stem Cell Research 2019;(7). DOI: 10.1016/j.scr.2019.101524
2. Chen PY, Lin YH, Liu TC, Lin YH, Tseng LH, Yang TH, Chen PL, Wu CC, Hsu CJ, 2019. Prediction model for audiological outcomes in patients with GJB2 mutations. Ear & Hearing 2019;(6). DOI: 10.1097/AUD.0000000000000742
3. Lin YH, Wu CC, Lin YH, Lu YC, Chen CS, Liu TC, Chen PL, Hsu CJ*, 2019. Targeted next-generation sequencing for genetic diagnosis in deaf families with enlarged vestibular aqueduct. Journal of Molecular Diagnostic 2019;21(1):138-148. [SCI]
4. Chan YH, Cheng YF, Chen YZ, Huang CY, Lin CH, Hu CJ, Lu YC, Wu CC*, Hus CJ*, 2018. Generation of induced pluripotent stem cells from a patient with hearing loss carrying GJB2 p.V37I mutation. Stem Cell Research 2018;33:51-55. [SCI]
5. Lin YH, Lin YH, Lu YC, Liu TC, Chen CY, Hsu CJ*, Chen PL*, Wu CC*, 2017. A novel missense variant in the nuclear localization signal of POU4F3 causes autosomal dominant non-syndromic hearing loss. Scientific Reports 2017;7 (1): 7551. doi:10.1038/s41598-017-08236-y.
6. Wu CC, Tsai CH, Hung CC, Lin YH, Lin YH, Huang FL, Tsao PN, Su YN, Yungling Leo Lee YL*, Hsieh WS*, Hsu CJ*, 2017. Newborn genetic screening for hearing impairment: A population-based longitudinal study. Genetics in Medicine 2017;19 (1):6-12. [SCI] doi:10.1038/gim.2016.66
7. Wu CC, Chen YH, Yang TH, Lin KN, Lee SY, Liu TC, Hsu CJ*, 2017. Endoscopic versus microscopic management of congenital ossicular chain anomalies: our experiences with 29 patients. Clinical Otolaryngology 2016/12, doi: 10.1111/coa.12778.
8. Wu CC, Tsai CH, Hung CC, Lin YH, Lin YH, Huang FL, Tsao PN, Su YN, Yungling Leo Lee YL*, Hsieh WS*, Hsu CJ*, 2016. Newborn genetic screening for hearing impairment: A population-based longitudinal study. Genetics in Medicine doi:10.1038/gim.2016.66.