Dr Ming Tsuang’s research interests are manifold. He has been recognized worldwide for his research in schizophrenia, manic-depressive illness, and substance abuse. His current research interests include the interactions between genetic and environmental risk factors for severe mental disorders and genetic linkage studies of schizophrenia through genome wide association studies (GWAS). The challenge of identifying the biomarkers of autism and posttraumatic stress disorder (PTSD), and the study of prevention as it relates to psychiatric disorders before their onset are also part of Dr Tsuang’s research portfolio. This research involves investigating the links between those suffering from mental illness and their blood relatives in order to identify traits that predispose a person to developing mental illnesses from both genetic and environmental perspectives. Dr Tsuang has also investigated the role of human disposition as it pertains to forgiveness and the roles of genetics and situation on the expression of the gene.
Dr Tsuang has published over 630 peer reviewed papers, 103 book chapters and 21 books in the areas of Psychiatric Genetics and Genomics; Psychiatric Epidemiology, Biomarkers and the neurobiology of major psychosis; Cognitive Neurosciences; Substance Abuse; early identification and intervention towards prevention of mental disorders; and spirituality & forgiveness.
1. Glatt SJ, Tylee DS, Chandler SD, Pazol J, Nievergelt CM, Woelk CH, Baker DG, Lohr JB, Kremen WS, Litz BT, Tsuang MT; Marine Resiliency Study Investigators. Blood-based gene-expression predictors of PTSD risk and resilience among deployed marines: a pilot study. Am J Med Genet B Neuropsychiatr Genet. 2013 Jun;162B(4):313-26.
2. Tsuang MT, Van Os J, Tandon R, Barch DM, Bustillo J, Gaebel W, Gur RE, Heckers S, Malaspina D, Owen MJ, Schultz S, Carpenter W. Attenuated Psychosis Syndrome in DSM-5 Schizophr Res. 2013 May 23
3. Woelk CH, Singhania A, Pérez-Santiago J, Glatt SJ, Tsuang MT. The utility of gene expression in blood cells for diagnosing neuropsychiatric disorders. Int Rev Neurobiol. 2011;101:41-63.