曾明宗

Ming-Tsung Tseng

Lab Introduction & Major Research Interests

My lab focuses on how humans percept pain and other somatosensory stimuli, such as warm, touch and itch. Using neuroimaging (MRI) complemented by electrophysiological and multidisciplinary techniques, we investigate the neural mechanisms of somatosensation in both physiological and pathological conditions along the neural axis, as well as how cognition and emotion modulate somatosensory processing in the human brain. We also explore topics in which pain or somatosensory stimulation serves as an important stimulus modality, such as perceptual decision making, empathy, and reinforcement learning. My long-term goal is to enhance the basic knowledge of perceptual neurosciences, and provide novel insights into the pathogenic mechanisms of somatosensory impairments, especially chronic pain.

Recent Representative Publication ( * corresponding author)

1. Shih YW, Tsai HY, Lin FS, Lin YH, Chiang CY, Lu ZL, Tseng MT*. Effects of positive and negative expectations on human pain perception engage separate but interrelated and dependently regulated cerebral mechanisms. J Neurosci. 2019;39:1261-1274.

2. Yang SL, Wu TW, Tseng MT*. Vigilance-related attention systems subserve the discrimination of relative intensity differences between painful stimuli. Pain. 2018;159:359-370.

3. Tseng MT*, Kong Y, Eippert F, Tracey I. Determining the neural substrate for encoding a memory of human pain and the influence of anxiety. J Neurosci. 2017;37:11806-11817.

4. Tseng MT*, Kong Y, Chiang MC, Chao CC, Tseng WY, Hsieh ST. Brain imaging signatures of the relationship between epidermal nerve fibers and heat pain perception. Neuroimage. 2015;122:288-97.